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Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 323-331 doi: 10.1007/s11684-008-0062-6

Abstract: Hypertension is characterized by vascular smooth muscle constriction and vascular remodeling involvingadapter protein CAS family, has been shown to be a critical cellular component that regulates various smoothEvidence for the role of CAS in the regulation of vascular smooth muscle contractility is presented.Contraction stimulation induces CAS phosphorylation on Tyr-410 in arterial smooth muscle, creating theThese new findings establish the important role of CAS in the modulation of vascular smooth muscle functions

Keywords： Contraction stimulation     phosphatase-proline     molecular structure     discovered     hypertension    

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Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Frontiers of Medicine 2017, Volume 11, Issue 3,   Pages 403-409 doi: 10.1007/s11684-017-0522-y

Abstract: TFPI is expressed by endothelial and smooth muscle cells in the vasculature.However, the role of endogenous TFPI in vascular smooth muscle cells (VSMCs) in thrombosis and vascular

Keywords： arterial thrombosis     conditional knockout mice     tissue factor pathway inhibitor     vascular smooth muscle    

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sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascularsmooth muscle cells

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 320-329 doi: 10.1007/s11684-016-0463-x

Abstract: Rat aortic vascular smooth muscle cells (VSMCs) were treated with phosphate buffer solution or 500 µ

Keywords： p-cresyl sulfate     atherosclerosis     plaque stability     vascular smooth muscle cell    

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Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved

Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 225-228 doi: 10.1007/s11684-010-0003-z

Abstract: bradykinin-B2 receptor as well as the possible involved signal transduction pathways in cultured rat aortic vascularsmooth muscle cells (VSMCs).

Keywords： bradykinin     vascular smooth muscle cells     signal transduction pathways    

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Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 177-180 doi: 10.1007/s11684-009-0021-x

Abstract: To evaluate the mechanism of vascular endothelial growth factor (VEGF) on the prevention of restenosisangioplasty, the recombinant adenovirus vector containing hVEGF cDNA was constructed and transfected into vascularsmooth muscle cells (VSMC) .

Keywords： vascular endothelial growth factors     restenosis     reactive oxygen species     endothelial cells     vascular smooth    

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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.cyclase (sGC)–3′,5′-cyclic guanosine monophosphate (cGMP)–protein kinase G (PKG) signaling pathway in vascularsmooth muscle cells (VSMCs) to dilate the arteries.These effects were eliminated by pre-incubating vascular rings with the sGC inhibitors NS 2028 or ODQsmooth muscle cells (MOVAs).

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Frontiers of Medicine 2015, Volume 9, Issue 4,   Pages 421-430 doi: 10.1007/s11684-015-0424-9

Abstract: /i>-glycoprotein expressed in diverse cell types, such as lymphatic endothelial cells (LECs) in the vascularIn the vascular system, normal expression of PDPN at the LEC surface requires transcriptional activationThis review provides a comprehensive overview of the roles of PDPN in vascular development and lymphoid

Keywords： podoplanin     CLEC-2     Prox1     O-glycosylation     lymphatic vascular development and maintenance     lymphoid    

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Extended model predictive control scheme for smooth path following of autonomous vehicles

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 1,   Pages 4-4 doi: 10.1007/s11465-021-0660-4

Abstract: extended MPC method solved by differential evolution optimization algorithm is proposed to realize optimal smoothResults indicate that the proposed method can obtain the smooth transition to follow the optimal drivable

Keywords： autonomous vehicles     vehicle dynamic modeling     model predictive control     path following     optimization algorithm    

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Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 398-400 doi: 10.1007/s11684-007-0077-4

Abstract: relationship between the expression of adrenomedullin (ADM) and microvessel density (MVD) and prognosis in smoothThe ADM is an important angiogenic factor in smooth muscle tumor of uterus.

Keywords： anticarcinogenic     microvessel density     malignant potency     muscle     uterine leiomyosarcoma    

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Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Frontiers of Medicine 2009, Volume 3, Issue 3,   Pages 284-286 doi: 10.1007/s11684-009-0062-1

Abstract: To evaluate the role of nitric oxide in the biological effects of vascular endothelial growth factor(VEGF) and the possible mechanism of VEGF, the cultured vascular endothelial cells of rabbit aorta wereThe absorbance () value of vascular endothelial cells and the levels of prostaglandin (PGI), endothelinVEGF could promote the proliferation and secretion of PGI and inhibit the secretion of ET-1 and vWF in vascularoxide is an important mediator in the process of stimulating proliferation and regulating secretion of vascular

Keywords： vascular endothelial growth factor     nitric oxide     N-nitro-L-arginine methyl ester     vascular endothelial    

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Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 67-78 doi: 10.1007/s11684-012-0176-8

Abstract: In 2001, Jain proposed tumor vascular normalization as an alternative approach to treating cancers basedPreclinical and clinical data have shown that tumor vascular normalization using monoclonal antibodiesHowever, current tumor vascular normalizing drugs display moderate anticancer efficacy.Therefore, multiple-targeting of vasculogenic tumor cells and genes may improve the efficacy of tumor vascularTo this end, the combination of antiangiogenic drugs with tumor vascular normalizing therapeutics, as

Keywords： angiogenesis     vasculogenesis     neovascularization     tumor     vasculature     normalization     traditional Chinese medicine    

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Preparation and gaseous photocatalytic activity of smooth potassium dititanate film

QIAN Qinghua, HU Yuyan, WEN Gaofei, FENG Xin, LU Xiao-hua

Frontiers of Chemical Science and Engineering 2008, Volume 2, Issue 3,   Pages 308-314 doi: 10.1007/s11705-008-0047-7

Abstract: A new smooth potassium dititanate film was prepared by sol-gel method and characterized by thermogravimetryThe gaseous photocatalytic activity of smooth KTiO films was studied using contact angle analysis fromIt was shown that the films were smooth, compact, and transparent when formed on glass.

Keywords： reflectance     UV-Visible     photocurrent     irradiation     scanning calorimetry    

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Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

Frontiers of Medicine 2018, Volume 12, Issue 5,   Pages 542-549 doi: 10.1007/s11684-017-0576-x

Abstract: (HSP20) is ubiquitously expressed under normal physiological conditions and has important roles in vascular

Keywords： preeclampsia     heat shock protein 20     vascular relaxation     coagulation-fibrinolytic system    

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High velocity impact of metal sphere on thin metallic plate using smooth particle hydrodynamics (SPH)

Hossein ASADI KALAMEH, Arash KARAMALI, Cosmin ANITESCU, Timon RABCZUK

Frontiers of Structural and Civil Engineering 2012, Volume 6, Issue 2,   Pages 101-110 doi: 10.1007/s11709-012-0160-z

Abstract: The modeling of high velocity impact is an important topic in impact engineering. Due to various constraints, experimental data are extremely limited. Therefore, detailed numerical simulation can be considered as a desirable alternative. However, the physical processes involved in the impact are very sophisticated; hence a practical and complete reproduction of the phenomena involves complicated numerical models. In this paper, we present a smoothed particle hydrodynamics (SPH) method to model two-dimensional impact of metal sphere on thin metallic plate. The simulations are applied to different materials (Aluminum, Lead and Steel); however the target and projectile are formed of similar metals. A wide range of velocities (300, 1000, 2000, and 3100 m/s) are considered in this study. The goal is to study the most sensitive input parameters (impact velocity and plate thickness) on the longitudinal extension of the projectile, penetration depth and damage crater.

Keywords： smoothed particle hydrodynamics     high velocity impact     sensitivity analysis    

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Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique

ZHANG Kaigang, ZENG Bingfang, ZHANG Changqing

Frontiers of Medicine 2007, Volume 1, Issue 2,   Pages 181-184 doi: 10.1007/s11684-007-0034-2

Abstract: The aim of this paper was to observe and visualize the changes in osteoblasts by electron microscopy during osteogenesis using tissue engineering technique. We also studied the feasibility of improving tissue vascularization of th

Keywords： feasibility     engineering     osteogenesis     vascularization     microscopy    

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Title Author Date Type Operation

Crk-associated substrate, vascular smooth muscle and hypertension

TANG Dale

Journal Article

Endogenous tissue factor pathway inhibitor in vascular smooth muscle cells inhibits arterial thrombosis

Jichun Yang, Kaiyue Jin, Jiajun Xiao, Jing Ma, Duan Ma

Journal Article

sulfate promotes the formation of atherosclerotic lesions and induces plaque instability by targeting vascularsmooth muscle cells

Hui Han,Yanjia Chen,Zhengbin Zhu,Xiuxiu Su,Jingwei Ni,Run Du,Ruiyan Zhang,Wei Jin

Journal Article

Effect of bradykinin on bradykinin-B2 receptor in rat aortic vascular smooth muscle cells and the involved

Wen YAN MD, Min FENG MD, Pei-Hua WANG MD, Dao-Wen WANG MD,

Journal Article

Mechanism of vascular endothelial growth factor on the prevention of restenosis after angioplasty

Qigong LIU, Honglian ZHOU, Yan ZENG, Shan YE, Jiani LIU, Zaiying LU

Journal Article

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Emerging roles of podoplanin in vascular development and homeostasis

Yanfang Pan,Lijun Xia

Journal Article

Extended model predictive control scheme for smooth path following of autonomous vehicles

Journal Article

Relationship of adrenomedullin expression and microvessel density and prognosis in smooth muscle tumor

JIANG Yuan, TIAN Xuehong, YUAN Jie, JIN Yuemei, TAN Yusong

Journal Article

Role of nitric oxide in biological effects of vascular endothelial growth factor

Qigong LIU M D , Yan ZENG , Jiani LIU , Shan YE , Yongdong LI , Zaiying LU M D ,

Journal Article

Progress in tumor vascular normalization for anticancer therapy: challenges and perspectives

Bingxue Shang, Zhifei Cao, Quansheng Zhou

Journal Article

Preparation and gaseous photocatalytic activity of smooth potassium dititanate film

QIAN Qinghua, HU Yuyan, WEN Gaofei, FENG Xin, LU Xiao-hua

Journal Article

Alteration of heat shock protein 20 expression in preeclamptic patients and its effect in vascular and

Fanfan Li, Mengzhou He, Meitao Yang, Yao Fan, Yun Chen, Xi Xia, Yin Xie, Dongrui Deng

Journal Article

High velocity impact of metal sphere on thin metallic plate using smooth particle hydrodynamics (SPH)

Hossein ASADI KALAMEH, Arash KARAMALI, Cosmin ANITESCU, Timon RABCZUK

Journal Article

Visualization of vascular ultrastructure during osteogenesis by tissue engineering technique

ZHANG Kaigang, ZENG Bingfang, ZHANG Changqing

Journal Article